Characterizations of Elephant Endotheliotropic Herpesvirus Type 1A and 4 Co-Infections in Asian Elephant (Elephas maximus) Calves

Characterizations of Elephant Endotheliotropic Herpesvirus Type 1A and 4 Co-Infections in Asian Elephant (Elephas maximus) Calves

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Three cases of double infection with elephant endotheliotropic herpesvirus (EEHV) types 1A and 4 in captive Asian elephants are presented.The first calf was a 4-year-old female that showed initial signs of lethargy and depression.The second calf was a 6-year-old female that displayed signs sex shop arles of depression and diarrhea and died within 48 h of the start of supportive treatment.

The third was a 2-year-old male that died suddenly while living with the herd.Necropsies were performed in the first and second elephants, while only a tongue sample was collected from the third calf.EEHV infection was confirmed via quantitative ngetikin PCR (qPCR) and gene sequencing, revealing double subtypes of EEHV1A and -4 infections.

This study describes the hematological and pathological characteristics within the host following double EEHV infection.